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PUREQUIMICA 4234

The Benchmark in Tablet Disintegration
Purequimica® 4234 is a high-performance tablet disintegrant that enhances the dissolution and bioavailability of solid dosage forms. This advanced ion exchange resin ensures rapid disintegration through superior swelling and wicking properties, making it an essential ingredient for optimized drug delivery.
  • Fast Disintegration Enhances tablet disintegration by swelling rapidly in aqueous solutions, ensuring quicker drug release for better bioavailability.
  • Effective Swelling Provides high swelling capacity, improving the breakdown of tablets in the gastrointestinal tract for faster absorption.
  • Versatile Application Suitable for direct compression, wet granulation, and dry granulation, ensuring compatibility with various formulation techniques.
  • Enhanced Drug Dissolution Optimizes drug release by wicking moisture into tablet pores, accelerating disintegration and improving patient compliance.
  • High Stability Maintains performance across different formulations, offering consistent disintegration properties without compromising drug stability.
  • Superior Performance Works effectively at low concentrations (1-10% of formulation), making it a cost-efficient and reliable excipient for solid dosage forms.
Application in products
Tablets & Capsule
  • Immediate-release tablets
  • Hard gelatin capsules
  • Liquid-filled capsules
Granules & Powders
  • Effervescent granules
  • Powdered drug formulations
Technical specifications 
  • Appearance: White to pale cream powder
  • Solubility: Insoluble in water and common solvents
  • Matrix: Copolymer of methacrylic acid and divinyl benzene
  • Functional Group: Carboxylic acid
  • pH (10% slurry): 7.0 – 9.0
Safety and Toxicology
  • Non-toxic under recommended use
  • Avoid inhalation of fine particles or dust
  • Use protective gear (gloves, goggles, mask) in industrial settings
Storage and Handling
  • Store in a cool, dry place (15°C – 30°C).
  • Maintain low humidity to prevent clumping.
  • Keep in tightly sealed containers to avoid contamination.
  • Prevent contamination – Keep away from moisture, acids, and strong oxidizers.
Packaging and Retesting
  • Sealed packaging to prevent contamination and moisture absorption.
  • Retest before use if stored beyond the recommended shelf life.
Frequently Asked Questions

Your questions our answers.

What are Purequimica® Excipients?
Purequimica® offers a portfolio of pharmacopeia-compliant excipients (USP, Ph. Eur., IP) designed to support solid, semi-solid, and liquid dosage formulations.
What dosage forms can they be used in?
• Solid: Tablets, capsules, powders, granules.
• Semi-solid: Creams, ointments, gels.
• Liquid: Syrups, suspensions, emulsions, oral solutions.
What are their main functional roles?
• Binders – for granulation and tablet strength.
• Disintegrants – for rapid drug release.
• Lubricants & Glidants – for efficient tablet compression.
• Suspending & Stabilizing agents – to maintain uniform dispersions.
• Viscosity enhancers & Gelling agents – for topical gels/creams.
• Solubilizers & Emulsifiers – for poorly soluble APIs.
What advantages do they offer?
• High purity and batch consistency
• Regulatory acceptance in global markets
• Versatility across dosage forms
• Improved processability and bioavailability support
Are they safe for pharmaceutical applications?
Yes. Purequimica® excipients comply with USP, Ph. Eur., and IP standards and are manufactured under strict GMP conditions.
How are they supplied?
Available in different grades and physical forms (like powders, liquids) tailored to the application.
Do you provide technical support?
Yes. We provides TDS, CoA and formulation guidance to support R&D and regulatory submissions.